Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 10/20 | 0.73 |
| ▸ | FLT1 | P17948 | 4/20 | 0.73 |
| ▸ | KDR | P35968 | 6/20 | 0.58 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.51 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.42 |
| ▸ | ILK | Q13418 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3533576 | 0.85 | FGFR1 (0.71) | FGFR1FLT1KDRPDGFRBGSK3B | |
| SCHEMBL31006247 | 0.85 | FGFR1 (0.71) | FGFR1FLT1KDRPDGFRBGSK3B | |
| SCHEMBL3535637 | 0.85 | FGFR1 (1.00) | FGFR1FLT1KDRPDGFRBGSK3B | |
| SCHEMBL31006249 | 0.84 | FGFR1 (0.67) | FGFR1FLT1KDRPDGFRBGSK3B | |
| SCHEMBL3533608 | 0.79 | FGFR1 (0.74) | FGFR1FLT1KDRPDGFRBGSK3B | |
| SCHEMBL3534013 | 0.78 | FGFR1 (0.76) | FGFR1FLT1KDRPDGFRBGSK3B | |
| SCHEMBL3541844 | 0.78 | FGFR1 (0.76) | FGFR1FLT1KDRPDGFRBGSK3B | |
| SCHEMBL29009526 | 0.76 | ITK (0.46) | FGFR1FLT1KDRGSK3BFGFR3 | |
| SCHEMBL31006258 | 0.76 | ITK (0.46) | FGFR1FLT1KDRGSK3BFGFR3 | |
| SCHEMBL31006255 | 0.76 | BRD4 (0.43) | FGFR1FLT1KDRPDGFRBGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217551-A | Substituted indazole or azaindazole compounds and application thereof | 河南中医药大学 | 2023-06-06 | — | — | CN | disclosed |