Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.82 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.82 |
| ▸ | MEN1 | O00255 | 6/20 | 0.82 |
| ▸ | GAA | P10253 | 2/20 | 0.75 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 9/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16788880 | 1.00 | KMT2A (0.82) | KMT2AL3MBTL1MEN1GAAKAT8 | |
| SCHEMBL28473982 | 1.00 | KMT2A (0.82) | KMT2AL3MBTL1MEN1GAAKAT8 | |
| SCHEMBL28967925 | 0.94 | KAT8 (0.78) | KMT2AL3MBTL1MEN1GAAKAT8 | |
| SCHEMBL28967929 | 0.94 | KAT8 (0.78) | KMT2AL3MBTL1MEN1GAAKAT8 | |
| SCHEMBL28967916 | 0.94 | KMT2A (0.81) | KMT2AL3MBTL1MEN1GAAKAT8 | |
| SCHEMBL10035997 | 0.94 | KMT2A (0.81) | KMT2AL3MBTL1MEN1GAAKAT8 | |
| SCHEMBL28476008 | 0.94 | KMT2A (0.81) | KMT2AL3MBTL1MEN1GAAKAT8 | |
| SCHEMBL13011253 | 0.90 | KMT2A (0.76) | KMT2AL3MBTL1MEN1GAAKAT8 | |
| SCHEMBL4382966 | 0.90 | KMT2A (0.76) | KMT2AL3MBTL1MEN1GAAKAT8 | |
| SCHEMBL446478 | 0.90 | KMT2A (0.76) | KMT2AL3MBTL1MEN1GAAKAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111871460-B | Thioamide small molecule catalyst based on C2 symmetry and pseudo C2 symmetry and synthesis and application thereof | 山西医科大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-111871460-A | Thioamide small molecule catalyst based on C2 symmetry and pseudo C2 symmetry, and synthesis and application thereof | 山西医科大学 | 2020-11-03 | — | — | CN | disclosed |