⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2903555 | 0.84 | MAPT (0.40) | — | |
| SCHEMBL2901249 | 0.77 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL1979312 | 0.68 | — | — | |
| SCHEMBL2902762 | 0.67 | — | — | |
| SCHEMBL6627153 | 0.60 | — | — | |
| SCHEMBL229616 | 0.59 | — | — | |
| SCHEMBL9870669 | 0.59 | MAPT (0.33) | — | |
| SCHEMBL27817332 | 0.56 | — | — | |
| SCHEMBL230963 | 0.56 | — | — | |
| SCHEMBL3878350 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| EP-2236505-A1 | Acylated aminopyridines and pyridazines as insecticides | Bayer CropScience AG (DE) | 2010-10-06 | — | — | EP | disclosed |