Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 9/20 | 0.55 |
| ▸ | HRH2 | P25021 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1059811 | 0.82 | PIK3CA (0.48) | PIK3CANPC1PIK3CGALDH1A1MAPT | |
| SCHEMBL30476481 | 0.82 | PIK3CA (0.48) | PIK3CANPC1PIK3CGALDH1A1MAPT | |
| SCHEMBL29011654 | 0.80 | PIK3CA (0.59) | PIK3CAPIK3CGPIK3CDPIK3CBGAK | |
| SCHEMBL1938188 | 0.78 | PIK3CA (0.55) | PIK3CANPC1PIK3CGALDH1A1MAPT | |
| SCHEMBL1938594 | 0.77 | PIK3CA (0.54) | PIK3CANPC1PIK3CGALDH1A1MAPT | |
| SCHEMBL1938764 | 0.76 | PIK3CA (0.48) | PIK3CAHRH2HRH1HRH4HRH3 | |
| SCHEMBL30500997 | 0.76 | PIK3CA (0.51) | PIK3CAPIK3CGPIK3CDPIK3CBGAK | |
| SCHEMBL15801542 | 0.76 | PIK3CA (0.51) | PIK3CAPIK3CGPIK3CDPIK3CBGAK | |
| SCHEMBL29011680 | 0.74 | PIK3CA (0.65) | PIK3CAPIK3CGPIK3CDPIK3CBGAK | |
| SCHEMBL24023236 | 0.73 | MEN1 (0.41) | PIK3CAHRH2HRH1HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116987073-A | PI3K alpha/HDAC 6 subtype selective dual inhibitor and application thereof | 嘉兴学院 | 2023-11-03 | — | — | CN | disclosed |
| CN-116239591-A | (4R) -sulfonamido-L-prolinamide compound, preparation method, application and pharmaceutical composition thereof | 嘉兴学院 | 2023-06-09 | — | — | CN | disclosed |