Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.39 |
| ▸ | FEN1 | P39748 | 3/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25031052 | 0.91 | MAPT (0.39) | FFAR4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30479044 | 0.91 | MAPT (0.39) | FFAR4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29013177 | 0.89 | FFAR4 (0.47) | S1PR5FFAR4FEN1GRM5NPC1 | |
| SCHEMBL30478992 | 0.88 | FFAR4 (0.40) | FFAR4FEN1GRM5ALOX5AP | |
| SCHEMBL25938994 | 0.88 | FFAR4 (0.40) | FFAR4FEN1GRM5ALOX5AP | |
| SCHEMBL25935253 | 0.83 | MAPT (0.40) | FFAR4SMN1; SMN2 | |
| SCHEMBL29013187 | 0.83 | GRM5 (0.38) | S1PR5FFAR4FEN1GRM5PTGDR2 | |
| SCHEMBL25419978 | 0.81 | FFAR4 (0.43) | FFAR4FEN1GRM5ALOX5AP | |
| SCHEMBL30475482 | 0.81 | MAPT (0.44) | FFAR4SMN1; SMN2 | |
| SCHEMBL25937000 | 0.81 | MAPT (0.44) | FFAR4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261458-B | PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-05-24 | — | — | CN | disclosed |
| CN-116261458-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2023-06-13 | — | — | CN | disclosed |