SCHEMBL29013205

SCHEMBL29013205

CC(O)CC(C(=O)O)N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
HDAC6 Q9UBN7 2/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
MAPK1 P28482 1/20 0.31
CTSL P07711 1/20 0.31
CTSB P07858 1/20 0.31
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31
AAK1 Q2M2I8 1/20 0.30
CYP2D6 P10635 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1763982 0.85 MEN1 (0.35) MEN1GAAKMT2AHDAC6HDAC1
SCHEMBL29273128 0.81 MEN1 (0.32) MEN1GAAKMT2AHDAC6HDAC1
SCHEMBL29013229 0.81 HDAC1 (0.32) HDAC6HDAC1HDAC2
SCHEMBL29013209 0.81 MEN1 (0.33) MEN1GAAKMT2AHDAC6HDAC1
SCHEMBL29013212 0.81 CA12 (0.34) MEN1GAAKMT2AHDAC6HDAC1
SCHEMBL15562529 0.81 MEN1 (0.33) MEN1GAAKMT2AHDAC6HDAC1
SCHEMBL15454789 0.81 MEN1 (0.33) MEN1GAAKMT2AHDAC6HDAC1
SCHEMBL30039435 0.80 MEN1 (0.35) MEN1GAAKMT2AHDAC6HDAC1
SCHEMBL28456427 0.79 MEN1 (0.34) MEN1GAAKMT2AHDAC6HDAC1
SCHEMBL28105502 0.79 MEN1 (0.34) MEN1GAAKMT2AHDAC6HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115850120-A Preparation method of alcohol alpha-carbon hydrogen bond alkylated compound 浙江工业大学 2023-03-28 CN disclosed