Sulfamate

Sulfamate

SCHEMBL29014379

CC(O)CNCCN.NS(=O)(=O)O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.41
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CA6 P23280 4/20 0.35
CA7 P43166 4/20 0.35
CA9 Q16790 4/20 0.35
CA5B Q9Y2D0 4/20 0.35
CA12 O43570 3/20 0.35
CA14 Q9ULX7 3/20 0.35
RECQL P46063 1/20 0.35
CA2 P00918 4/20 0.33
GRIA1 P42261 3/20 0.33
TDP1 Q9NUW8 3/20 0.33
CA4 P22748 3/20 0.33
CA5A P35218 3/20 0.33
LMNA P02545 2/20 0.33
CA3 P07451 2/20 0.33
CA1 P00915 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfamate SCHEMBL30352769 0.90 KMT2A (0.39) ANPEPKMT2AMEN1RAB9ASMN1; SMN2
Sulfamate SCHEMBL30352768 0.90 KMT2A (0.39) ANPEPKMT2AMEN1RAB9ASMN1; SMN2
SCHEMBL19774600 0.87
SCHEMBL169586 0.87
SCHEMBL28573042 0.87 ANPEP (0.38) ANPEPKMT2AMEN1RAB9ASMN1; SMN2
SCHEMBL27794421 0.85
SCHEMBL11014748 0.85 CA12 (0.48) ANPEPKMT2AMEN1RAB9ASMN1; SMN2
Sulfamate SCHEMBL28991733 0.84 KMT2A (0.33) KMT2AMEN1RAB9ASMN1; SMN2CA6
SCHEMBL9733941 0.83 CA12 (0.52) ANPEPKMT2AMEN1RAB9ASMN1; SMN2
SCHEMBL5425015 0.83 CA12 (0.52) ANPEPKMT2AMEN1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116023281-A Hydroxyalkyl tertiary amine sulfamate, crystal, preparation method and application thereof 南京红宝丽醇胺化学有限公司 2023-04-28 CN claimed
CN-116023281-A Hydroxyalkyl tertiary amine sulfamate, crystal, preparation method and application thereof 南京红宝丽醇胺化学有限公司 2023-04-28 CN disclosed