Sulfamate

Sulfamate

SCHEMBL29014390

CCC(N)(N)CC(C)O.NS(=O)(=O)O

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
NT5E P21589 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
HIF1A Q16665 1/20 0.32
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3144766 0.87
SCHEMBL11725261 0.72 TSHR (0.40) TSHRCYP1A2CYP3A4CYP2C9HIF1A
SCHEMBL5972431 0.72 TSHR (0.40) TSHRCYP1A2CYP3A4CYP2C9HIF1A
Sulfuric Acid SCHEMBL27903547 0.71 HIF1A (0.53) CYP1A2CYP3A4CYP2C9HIF1ATP53
SCHEMBL9332197 0.69
SCHEMBL29574510 0.69 CYP1A2 (0.36) TSHRCYP1A2CYP3A4CYP2C9HIF1A
SCHEMBL5545041 0.68 CYP1A2 (0.33) CYP1A2CYP3A4CYP2C9HIF1A
Sulfamate SCHEMBL28304617 0.68
SCHEMBL27768536 0.67
SCHEMBL18173861 0.67 CYP1A2 (0.32) CYP1A2CYP3A4CYP2C9HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116023281-A Hydroxyalkyl tertiary amine sulfamate, crystal, preparation method and application thereof 南京红宝丽醇胺化学有限公司 2023-04-28 CN claimed
CN-116023281-A Hydroxyalkyl tertiary amine sulfamate, crystal, preparation method and application thereof 南京红宝丽醇胺化学有限公司 2023-04-28 CN disclosed