Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29014551 | 0.89 | GAA (0.48) | GAAMEN1KMT2ALMNATSHR | |
| SCHEMBL28303559 | 0.84 | KCNH2 (0.43) | GAAMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL29014518 | 0.84 | KCNH2 (0.48) | GAAKCNH2 | |
| SCHEMBL30482810 | 0.84 | KCNH2 (0.48) | GAAKCNH2 | |
| SCHEMBL28302265 | 0.84 | KCNH2 (0.46) | GAALMNATSHRMAPTKCNH2 | |
| SCHEMBL29014509 | 0.82 | MEN1 (0.52) | GAAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL253511 | 0.81 | GAA (0.53) | GAAMEN1KMT2ALMNATSHR | |
| SCHEMBL29014527 | 0.78 | GAA (0.59) | GAAMEN1KMT2ALMNATSHR | |
| SCHEMBL29014516 | 0.77 | KMT2A (0.48) | GAAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL1917727 | 0.76 | GAA (0.48) | GAAMEN1KMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109942523-B | Benzofuran and benzofuran coumarin derivatives, and preparation method and application thereof | 华东师范大学 | 2023-06-09 | — | — | CN | disclosed |