Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 12/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 11/20 | 0.41 |
| ▸ | TSHR | P16473 | 10/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 7/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PDE9A | O76083 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 5/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30452410 | 0.91 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL24252929 | 0.91 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL30451317 | 0.89 | CYP1A2 (0.46) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL24252808 | 0.89 | CYP1A2 (0.46) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL30467633 | 0.85 | CYP1A2 (0.39) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL24252915 | 0.85 | CYP1A2 (0.39) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL30467726 | 0.85 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL24252454 | 0.85 | CYP1A2 (0.41) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL30451677 | 0.85 | CYP1A2 (0.41) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL29015506 | 0.84 | PDE4A (0.39) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |