⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1616141 | 0.91 | — | — | |
| SCHEMBL30701397 | 0.88 | TSHR (0.44) | — | |
| SCHEMBL27033085 | 0.88 | TSHR (0.44) | — | |
| SCHEMBL29074323 | 0.88 | TSHR (0.44) | — | |
| SCHEMBL9248456 | 0.88 | — | — | |
| SCHEMBL6364555 | 0.88 | TSHR (0.44) | — | |
| SCHEMBL2645410 | 0.80 | — | — | |
| SCHEMBL8814930 | 0.79 | — | — | |
| Hexane SCHEMBL7134957 | 0.76 | TSHR (0.50) | — | |
| SCHEMBL19146515 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754591-B | HDAC, JAK and BET three-target inhibitor and preparation method and application thereof | 山东大学 | 2024-01-05 | — | — | CN | claimed |
| CN-113754591-B | HDAC, JAK and BET three-target inhibitor and preparation method and application thereof | 山东大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-113929605-B | Ortho-sulfonylated arylamine compound and synthesis method thereof | 山东大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-108409615-B | Method for synthesizing enantiopure tert-butyl sulfenamide | 大连双硼医药化工有限公司 | 2020-09-11 | — | — | CN | disclosed |
| CN-108467353-B | Preparation method of enantiopure tert-butyl sulfinamide | 大连双硼医药化工有限公司 | 2020-09-11 | — | — | CN | disclosed |
| CN-108558715-B | Method for preparing enantiopure tert-butyl sulfenamide | 上海平创化工科技有限公司 | 2020-08-07 | — | — | CN | disclosed |
| CN-110050331-A | thermal atomic layer etching process | ASM IP 控股有限公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-109843866-A | YAP1 inhibitors targeting YAP1 interaction with OCT4 | H·李·莫菲特癌症中心研究有限公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-107459532-B | A kind of new Anti-cancer medicament intermediate | 重庆南松凯博生物制药有限公司 | 2019-05-28 | — | — | CN | disclosed |
| CN-106478607-B | Substituted heteroaryl compound and combinations thereof and purposes | 广东东阳光药业有限公司 | 2019-05-24 | — | — | CN | disclosed |
| US-6573278-B2 | For therapy and prophylaxis of cerebral apoplexy and craniocerebral trauma | BAYER AKTIENGESELLSCHAFT (DE) | 2003-06-03 | — | — | US | disclosed |
| EP-0966436-B1 | ARYL SULFONAMIDES AND ANALOGUES THEREOF AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | BAYER AG (DE) | 2002-12-11 | — | — | EP | disclosed |
| US-20020072529-A1 | Arylsulfonamides and analogues | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2002-06-13 | — | — | US | disclosed |
| US-6262112-B1 | 1-(4,4,4-TRIFLUOROBUTYLSULPHONYLOXY)-3-(2-(HYDROXYMETHYL)INDAN -4-YLOXY)-BENZENE | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-17 | — | — | US | disclosed |
| US-5574131-A | REACTED WITH AN ACYL HALIDE, SOLUBILITY | TOMOEGAWA PAPER CO., LTD. (JP) | 1996-11-12 | — | — | US | disclosed |
| EP-0455224-B1 | Polyaniline derivatives and their production process | TOMOEGAWA PAPER CO LTD (JP) | 1996-08-14 | — | — | EP | disclosed |
| US-5254670-A | Polyaniline derivatives and their production process | TOMOEGAWA PAPER CO., LTD. (JP) | 1993-10-19 | — | — | US | disclosed |
| EP-0455224-A2 | Polyaniline derivatives and their production process | TOMOEGAWA PAPER CO. LTD. (JP) | 1991-11-06 | — | — | EP | disclosed |
| US-4584371-A | Catalytic process for preparing 3-ester-methyl cephalosporins from desacetyl-7-aminocephalosporanic acid | THE UPJOHN COMPANY (US) | 1986-04-22 | — | — | US | disclosed |
| EP-0153874-A2 | Cephalosporin intermediates and their preparation | THE UPJOHN COMPANY (US) | 1985-09-04 | — | — | EP | disclosed |