Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30370795 | 1.00 | KDM4E (0.50) | KDM4ENFKB1NFKB2RELALMNA | |
| SCHEMBL30370488 | 0.81 | SRD5A2 (0.52) | KDM4ENFKB1NFKB2RELALMNA | |
| SCHEMBL29016622 | 0.81 | SRD5A2 (0.52) | KDM4ENFKB1NFKB2RELALMNA | |
| SCHEMBL29016584 | 0.80 | CYP2C9 (0.45) | POLBNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL29016610 | 0.80 | APP (0.54) | KDM4ESMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL30370846 | 0.80 | CYP2C9 (0.45) | POLBNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL30370212 | 0.80 | APP (0.54) | KDM4ESMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL28946486 | 0.79 | KDM4E (0.54) | KDM4ENFKB1NFKB2RELALMNA | |
| SCHEMBL30076455 | 0.79 | KDM4E (0.54) | KDM4ENFKB1NFKB2RELALMNA | |
| SCHEMBL29016628 | 0.78 | KDM4E (0.47) | KDM4ENFKB1NFKB2RELALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689942-B | Nitrogen-containing bicyclic compound, and preparation method and application thereof | 广东东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |