Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 3/20 | 0.43 |
| ▸ | APP | P05067 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30370454 | 0.85 | PPARA (0.40) | MAPTRAB9ANPC1GAAAPP | |
| SCHEMBL29016596 | 0.85 | PPARA (0.40) | MAPTRAB9ANPC1GAAAPP | |
| SCHEMBL29016677 | 0.82 | SMN1; SMN2 (0.54) | MAPTRAB9ANPC1GAAKDM4E | |
| SCHEMBL30370019 | 0.82 | SMN1; SMN2 (0.54) | MAPTRAB9ANPC1GAAKDM4E | |
| SCHEMBL29016628 | 0.81 | KDM4E (0.47) | MAPTRAB9ANPC1GAAKDM4E | |
| SCHEMBL30370793 | 0.81 | KDM4E (0.47) | MAPTRAB9ANPC1GAAKDM4E | |
| SCHEMBL29016598 | 0.78 | EPHX2 (0.51) | MAPTRAB9ANPC1GAAKDM4E | |
| SCHEMBL30370205 | 0.78 | EPHX2 (0.51) | MAPTRAB9ANPC1GAAKDM4E | |
| SCHEMBL30370212 | 0.75 | APP (0.54) | MAPTRAB9ANPC1GAAKDM4E | |
| SCHEMBL29016610 | 0.75 | APP (0.54) | MAPTRAB9ANPC1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689942-B | Nitrogen-containing bicyclic compound, and preparation method and application thereof | 广东东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |