Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 10/20 | 0.73 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25278519 | 1.00 | HTR1B (0.73) | HTR1BCHRM2CHRM1CHRM3LMNA | |
| Hydrochloric Acid SCHEMBL25238177 | 0.98 | HTR1B (0.71) | HTR1BCHRM2CHRM1CHRM3LMNA | |
| Hydrochloric Acid SCHEMBL25236578 | 0.98 | HTR1B (0.71) | HTR1BCHRM2CHRM1CHRM3LMNA | |
| SCHEMBL25281414 | 0.88 | HTR1B (0.73) | HTR1BCHRM2CHRM1CHRM3TSHR | |
| SCHEMBL29016973 | 0.88 | HTR1B (0.73) | HTR1BCHRM2CHRM1CHRM3TSHR | |
| SCHEMBL25276454 | 0.88 | HTR1B (0.73) | HTR1BCHRM2CHRM1CHRM3TSHR | |
| Hydrochloric Acid SCHEMBL25278919 | 0.87 | HTR1B (0.71) | HTR1BCHRM2CHRM1CHRM3LMNA | |
| SCHEMBL24111276 | 0.84 | HTR1B (1.00) | HTR1BSLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL24111395 | 0.84 | HTR1B (1.00) | HTR1BSLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL24111392 | 0.84 | HTR1B (1.00) | HTR1BSLC6A4SLC6A2SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075300-A | Advantageous benzofuran compositions for mental disorders or mental enhancement | 泰科根公司 | 2023-05-05 | — | — | CN | disclosed |