SCHEMBL29017448

SCHEMBL29017448

Clc1ccc2scc(Cl)c2c1

nearest known ligand 0.64

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.64
KEAP1 Q14145 1/20 0.51
NFE2L2 Q16236 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.46
CA2 P00918 1/20 0.46
MAPT P10636 7/20 0.42
LMNA P02545 2/20 0.42
TP53 P04637 2/20 0.42
KDM4E B2RXH2 1/20 0.40
ROCK1 Q13464 1/20 0.39
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30163349 0.82 CYP2A6 (0.48) CYP2A6KEAP1NFE2L2SMN1; SMN2CA2
SCHEMBL7917778 0.80 CYP2A6 (0.62) CYP2A6KEAP1NFE2L2SMN1; SMN2CA2
SCHEMBL3682441 0.80 CYP2A6 (0.62) CYP2A6KEAP1NFE2L2SMN1; SMN2CA2
SCHEMBL10411294 0.78 CYP2A6 (0.60) CYP2A6KEAP1NFE2L2SMN1; SMN2CA2
SCHEMBL422138 0.78 CYP2A6 (0.50) CYP2A6CA2MAPTLMNATP53
SCHEMBL6808185 0.78 CYP2A6 (0.55) CYP2A6KEAP1NFE2L2CA2MAPT
SCHEMBL167540 0.78 CYP2A6 (1.00) CYP2A6KEAP1NFE2L2SMN1; SMN2CA2
SCHEMBL2092745 0.78 CYP2A6 (0.60) CYP2A6KEAP1NFE2L2SMN1; SMN2CA2
SCHEMBL18379175 0.78 CYP2A6 (0.60) CYP2A6KEAP1NFE2L2SMN1; SMN2CA2
SCHEMBL25907075 0.78 CYP2A6 (0.60) CYP2A6KEAP1NFE2L2SMN1; SMN2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114414549-B Magnetic SERS (surface enhanced Raman scattering) encoded photonic crystal microsphere as well as preparation method and application thereof 河南大学 2023-06-23 CN claimed
CN-114414549-B Magnetic SERS (surface enhanced Raman scattering) encoded photonic crystal microsphere as well as preparation method and application thereof 河南大学 2023-06-23 CN disclosed