SCHEMBL29017666

SCHEMBL29017666

COC(=O)[C@H](Cc1ccccc1)NC(=O)CCC(=O)O

nearest known ligand 0.72

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 5/20 0.63
HDAC6 Q9UBN7 5/20 0.63
ATM Q13315 1/20 0.62
ALDH1A1 P00352 3/20 0.60
THRB P10828 1/20 0.60
CYP2C9 P11712 1/20 0.60
CYP2C19 P33261 1/20 0.60
HSD17B10 Q99714 1/20 0.60
POLB P06746 2/20 0.60
LMNA P02545 2/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
PARP1 P09874 1/20 0.57
PARP3 Q9Y6F1 1/20 0.57
GLA P06280 1/20 0.56
MDM4 O15151 1/20 0.56
MDM2 Q00987 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31527894 1.00 HDAC1 (0.63) HDAC1HDAC6ATMALDH1A1THRB
SCHEMBL19051497 0.92 HDAC1 (0.67) HDAC1HDAC6ATMALDH1A1THRB
SCHEMBL4145473 0.88 HDAC1 (0.63) HDAC1HDAC6ATMALDH1A1THRB
SCHEMBL4145476 0.88 HDAC1 (0.63) HDAC1HDAC6ATMALDH1A1THRB
SCHEMBL9487603 0.88 POLB (0.67) HDAC1HDAC6ATMALDH1A1THRB
SCHEMBL5966500 0.88 HDAC1 (0.63) HDAC1HDAC6ATMALDH1A1THRB
SCHEMBL9487610 0.88 POLB (0.67) HDAC1HDAC6ATMALDH1A1THRB
SCHEMBL23201833 0.87 PSMB5 (0.62) HDAC1HDAC6ATMALDH1A1THRB
SCHEMBL9755298 0.87 HDAC1 (0.62) HDAC1HDAC6ATMALDH1A1THRB
SCHEMBL21583794 0.87 PSMB5 (0.62) HDAC1HDAC6ATMALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116268354-B Neotame peculiar smell modifier, atomized essence and aerosol generating device 深圳昱朋科技有限公司 2024-03-26 CN disclosed
CN-116268354-A Neotame peculiar smell modifier, atomized essence and aerosol generating device 深圳昱朋科技有限公司 2023-06-23 CN disclosed