Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.86 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.79 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.70 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.69 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.69 |
| ▸ | TUBB | P07437 | 3/20 | 0.69 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.69 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.69 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.69 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.69 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.69 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.69 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.69 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.69 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.69 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.69 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.69 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.69 |
| ▸ | KRAS | P01116 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29018483 | 1.00 | ABCG2 (0.86) | ABCG2TNFRSF1AABCB1TUBB1TUBB4A | |
| SCHEMBL12484514 | 0.88 | TNFRSF1A (1.00) | ABCG2TNFRSF1AABCB1TUBB1TUBB4A | |
| SCHEMBL12484518 | 0.88 | TNFRSF1A (1.00) | ABCG2TNFRSF1AABCB1TUBB1TUBB4A | |
| SCHEMBL10497922 | 0.87 | ABCG2 (0.88) | ABCG2TNFRSF1AABCB1TUBB1TUBB4A | |
| SCHEMBL6659039 | 0.87 | ABCG2 (0.88) | ABCG2TNFRSF1AABCB1TUBB1TUBB4A | |
| SCHEMBL6780730 | 0.87 | ABCG2 (0.88) | ABCG2TNFRSF1AABCB1TUBB1TUBB4A | |
| SCHEMBL6780724 | 0.87 | ABCG2 (0.88) | ABCG2TNFRSF1AABCB1TUBB1TUBB4A | |
| SCHEMBL615819 | 0.87 | ABCG2 (0.88) | ABCG2TNFRSF1AABCB1TUBB1TUBB4A | |
| SCHEMBL8461357 | 0.87 | ABCG2 (0.88) | ABCG2TNFRSF1AABCB1LMNAMAPT | |
| SCHEMBL8461354 | 0.87 | ABCG2 (0.88) | ABCG2TNFRSF1AABCB1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116284025-A | Spiro heterocyclic compound with anticancer effect, pharmaceutical composition and application thereof | 国科大杭州高等研究院 | 2023-06-23 | — | — | CN | disclosed |