Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.97 |
| ▸ | MAPT | P10636 | 4/20 | 0.97 |
| ▸ | GLA | P06280 | 1/20 | 0.97 |
| ▸ | HTT | P42858 | 4/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | RRM1 | P23921 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1898236 | 0.99 | KDM4E (1.00) | KDM4EMAPTGLAHTTGAA | |
| SCHEMBL6639066 | 0.99 | KDM4E (1.00) | KDM4EMAPTGLAHTTGAA | |
| SCHEMBL30471385 | 0.97 | KDM4E (0.97) | KDM4EMAPTGLAHTTGAA | |
| SCHEMBL6746917 | 0.85 | KDM4E (0.76) | KDM4EMAPTGLAHTTRRM1 | |
| SCHEMBL6746916 | 0.85 | KDM4E (0.76) | KDM4EMAPTGLAHTTRRM1 | |
| Hydrochloric Acid SCHEMBL6741355 | 0.84 | KDM4E (0.74) | KDM4EMAPTGLAHTTRRM1 | |
| SCHEMBL20080878 | 0.84 | KDM4E (0.74) | KDM4EMAPTGLAHTTRRM1 | |
| Hydrochloric Acid SCHEMBL6741358 | 0.84 | KDM4E (0.74) | KDM4EMAPTGLAHTTRRM1 | |
| Hydrochloric Acid SCHEMBL7112094 | 0.83 | KDM4E (0.72) | KDM4EMAPTGLAHTTRRM1 | |
| Hydrochloric Acid SCHEMBL7112090 | 0.83 | KDM4E (0.72) | KDM4EMAPTGLAHTTRRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514873-B | Iridium compound with 2-hydroxy-1-naphthaldehyde thiosemicarbazone as ligand and synthetic method and application thereof | 广西科技师范学院 | 2024-09-20 | — | — | CN | claimed |
| CN-116514873-A | Iridium compound with 2-hydroxy-1-naphthaldehyde thiosemicarbazone as ligand and synthetic method and application thereof | 广西科技师范学院 | 2023-08-01 | — | — | CN | claimed |
| CN-116284150-A | 2-hydroxy-1-naphthaldehyde thiosemicarbazone iridium (III) complex and preparation method and application thereof | 广西科技师范学院 | 2023-06-23 | — | — | CN | claimed |
| CN-116514873-B | Iridium compound with 2-hydroxy-1-naphthaldehyde thiosemicarbazone as ligand and synthetic method and application thereof | 广西科技师范学院 | 2024-09-20 | — | — | CN | disclosed |
| CN-116514873-B | Iridium compound with 2-hydroxy-1-naphthaldehyde thiosemicarbazone as ligand and synthetic method and application thereof | 广西科技师范学院 | 2024-09-20 | — | — | CN | disclosed |
| CN-116514873-B | Iridium compound with 2-hydroxy-1-naphthaldehyde thiosemicarbazone as ligand and synthetic method and application thereof | 广西科技师范学院 | 2024-09-20 | — | — | CN | disclosed |
| CN-116514873-A | Iridium compound with 2-hydroxy-1-naphthaldehyde thiosemicarbazone as ligand and synthetic method and application thereof | 广西科技师范学院 | 2023-08-01 | — | — | CN | disclosed |
| CN-116514873-A | Iridium compound with 2-hydroxy-1-naphthaldehyde thiosemicarbazone as ligand and synthetic method and application thereof | 广西科技师范学院 | 2023-08-01 | — | — | CN | disclosed |
| CN-116514873-A | Iridium compound with 2-hydroxy-1-naphthaldehyde thiosemicarbazone as ligand and synthetic method and application thereof | 广西科技师范学院 | 2023-08-01 | — | — | CN | disclosed |
| CN-116284150-A | 2-hydroxy-1-naphthaldehyde thiosemicarbazone iridium (III) complex and preparation method and application thereof | 广西科技师范学院 | 2023-06-23 | — | — | CN | disclosed |
| CN-116284150-A | 2-hydroxy-1-naphthaldehyde thiosemicarbazone iridium (III) complex and preparation method and application thereof | 广西科技师范学院 | 2023-06-23 | — | — | CN | disclosed |
| CN-116284150-A | 2-hydroxy-1-naphthaldehyde thiosemicarbazone iridium (III) complex and preparation method and application thereof | 广西科技师范学院 | 2023-06-23 | — | — | CN | disclosed |