Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5842280 | 0.89 | TSHR (0.94) | TSHRALDH1A1CYP3A4MAPK1AR | |
| Ethane SCHEMBL27508988 | 0.86 | TSHR (0.90) | TSHRALDH1A1CYP3A4MAPK1AR | |
| Methyl Alcohol SCHEMBL28055239 | 0.86 | TSHR (0.90) | TSHRALDH1A1CYP3A4MAPK1AR | |
| SCHEMBL30631964 | 0.86 | — | — | |
| SCHEMBL134755 | 0.86 | — | — | |
| Ethane SCHEMBL27730863 | 0.84 | TSHR (0.85) | TSHRALDH1A1CYP3A4MAPK1AR | |
| Methylene Chloride SCHEMBL29241646 | 0.84 | TSHR (0.85) | TSHRALDH1A1CYP3A4MAPK1AR | |
| SCHEMBL31006506 | 0.84 | TSHR (0.94) | TSHRALDH1A1CYP3A4MAPK1AR | |
| Methane SCHEMBL28589037 | 0.84 | TSHR (0.94) | TSHRALDH1A1CYP3A4MAPK1AR | |
| Hydrochloric Acid SCHEMBL9797291 | 0.84 | TSHR (0.94) | TSHRALDH1A1CYP3A4MAPK1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116284852-A | PH sensitive interpenetrating network hydrogel | 广州医科大学附属肿瘤医院 | 2023-06-23 | — | — | CN | disclosed |