Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10881985 | 1.00 | CYP1A2 (0.61) | CYP1A2HTTMAPK1LMNAMAPT | |
| Ammonia Solution, Strong SCHEMBL689616 | 0.97 | CYP1A2 (0.58) | CYP1A2HTTMAPK1LMNAMAPT | |
| SCHEMBL10485824 | 0.93 | CYP1A2 (0.54) | CYP1A2HTTMAPK1LMNAMAPT | |
| SCHEMBL10701936 | 0.93 | CYP1A2 (0.54) | CYP1A2HTTMAPK1LMNAMAPT | |
| SCHEMBL8219465 | 0.93 | CYP1A2 (0.54) | CYP1A2HTTMAPK1LMNAMAPT | |
| SCHEMBL10485828 | 0.93 | CYP1A2 (0.54) | CYP1A2HTTMAPK1LMNAMAPT | |
| SCHEMBL10974028 | 0.92 | CYP1A2 (0.52) | CYP1A2HTTMAPK1LMNAMAPT | |
| SCHEMBL3293288 | 0.92 | CYP1A2 (0.52) | CYP1A2HTTMAPK1LMNAMAPT | |
| SCHEMBL10772877 | 0.90 | CYP1A2 (0.50) | CYP1A2HTTMAPK1LMNAMAPT | |
| SCHEMBL19125970 | 0.90 | CYP1A2 (0.50) | CYP1A2HTTMAPK1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4347597-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2024-04-10 | — | — | EP | claimed |
| CN-117377674-A | Pyrazolo [1,5-a ] pyrimidine compounds for the treatment of dermatological disorders | 大塚制药株式会社 | 2024-01-09 | — | — | CN | claimed |
| WO-2022255408-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-12-08 | — | — | WO | claimed |
| EP-0791025-B1 | AQUEOUS TWO-COMPONENT POLYURETHANE COATING AGENT, METHOD FOR PREPARING IT AND ITS USE IN MULTICOAT PAINTING PROCESSES | BASF COATINGS AG (DE) | 2001-12-19 | — | — | EP | claimed |
| EP-4347597-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2024-04-10 | — | — | EP | disclosed |
| CN-117377674-A | Pyrazolo [1,5-a ] pyrimidine compounds for the treatment of dermatological disorders | 大塚制药株式会社 | 2024-01-09 | — | — | CN | disclosed |
| EP-4219473-A1 | CRYSTAL TYPE II OF MALANOCORTIN RECEPTOR AGONIST COMPOUND AND METHOD FOR PREPARING SAME | Lg Chem, Ltd. (KR) | 2023-08-02 | — | — | EP | disclosed |
| US-20230190940-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-06-22 | — | — | US | disclosed |
| WO-2022255408-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-12-08 | — | — | WO | disclosed |
| EP-2154970-B1 | DI-SUBSTITUTED AMIDES FOR ENHANCING GLUTAMATERGIC SYNAPTIC RESPONSES | RESPIRERX PHARMACEUTICALS INC (US) | 2017-10-25 | — | — | EP | disclosed |
| US-20170101659-A1 | METHODS FOR INCREASING MOLECULAR DIVERSITY OF POLYKETIDES AND NON-RIBOSOMAL PROTEINS | Isomerase Therapeutics Ltd. (GB) | 2017-04-13 | — | — | US | disclosed |
| CN-104995255-A | Curable composition and color filter | FUJIFILM CORP | 2015-10-21 | — | — | CN | disclosed |
| EP-1184396-A1 | (Meth)acrylate ester-based resin composition | Nippon Shokubai Co., Ltd. (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-5582774-A | PHTHALOCYANINE DERIVATIVE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1996-12-10 | — | — | US | disclosed |
| US-5446141-A | Optical recording media, filters, liquid crystals display | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-08-29 | — | — | US | disclosed |
| EP-0337209-B1 | ALKYLPHTHALOCYANINE NEAR-INFRARED ABSORBERS AND RECORDING/DISPLAY MATERIALS USING THE SAME | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-08-04 | — | — | EP | disclosed |
| EP-0290391-B1 | POLYOLEFINES STABILIZED AGAINST LIGHT DEGRADATION | CIBA-GEIGY AG (CH) | 1992-06-10 | — | — | EP | disclosed |
| US-5024926-A | Heat, light, weather resistance; for optical recording media, filters, liquid crystal displays | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-06-18 | — | — | US | disclosed |
| EP-0337209-A2 | Alkylphthalocyanine near-infrared absorbers and recording/display materials using the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-10-18 | — | — | EP | disclosed |
| EP-0290391-A2 | Polyolefines stabilized against light degradation | CIBA-GEIGY AG (CH) | 1988-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230190940-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | CYP1A2 3570/4885HTT 2464/4885MAPK1 2017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.