Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 11/20 | 0.71 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6525871 | 0.86 | PTGIR (0.63) | PTGIRPTGDRCHRM3CHRM2CHRM1 | |
| SCHEMBL29019387 | 0.85 | PTGIR (0.70) | PTGIRPTGDRCHRM3CHRM2CHRM1 | |
| SCHEMBL1118700 | 0.84 | PTGIR (1.00) | PTGIRPTGDRBCHEACHENPC1 | |
| SCHEMBL1118698 | 0.84 | PTGIR (1.00) | PTGIRPTGDRBCHEACHENPC1 | |
| SCHEMBL23852045 | 0.82 | PTGIR (0.67) | PTGIRPTGDRCHRM3CHRM2CHRM1 | |
| SCHEMBL6516172 | 0.82 | PTGIR (0.60) | PTGIRPTGDRCHRM3CHRM2CHRM1 | |
| SCHEMBL29019400 | 0.82 | PTGIR (0.67) | PTGIRPTGDRCHRM3CHRM2CHRM1 | |
| SCHEMBL29019412 | 0.82 | PTGIR (0.73) | PTGIRPTGDRCHRM3CHRM2CHRM1 | |
| SCHEMBL29019409 | 0.82 | PTGIR (0.65) | PTGIRPTGDR | |
| SCHEMBL6517591 | 0.81 | PTGIR (0.79) | PTGIRPTGDRBCHEACHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003123-B | Modulators of the PGI2 receptor for the treatment of prostacyclin (PGI 2) receptor related disorders | 艾尼纳制药公司 | 2023-06-23 | — | — | CN | disclosed |