Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 12/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29019374 | 0.90 | PTGIR (0.56) | PTGIRCHRM3CHRM2CHRM1PTGDR | |
| SCHEMBL29019384 | 0.90 | PTGIR (0.58) | PTGIRCHRM3CHRM2CHRM1PTGDR | |
| SCHEMBL29019383 | 0.89 | PTGIR (0.59) | PTGIRCHRM3CHRM2CHRM1PTGDR | |
| SCHEMBL29019391 | 0.88 | PTGIR (0.56) | PTGIRCHRM3CHRM2CHRM1PTGDR | |
| SCHEMBL29019403 | 0.86 | PTGIR (0.68) | PTGIRCHRM3CHRM2CHRM1PTGDR | |
| SCHEMBL29019399 | 0.85 | PTGIR (0.60) | PTGIRCHRM3PTGDRMGLL | |
| SCHEMBL29019382 | 0.84 | PTGIR (0.56) | PTGIRCHRM3PTGDRMGLL | |
| SCHEMBL29019405 | 0.84 | PTGIR (0.58) | PTGIRCHRM3PTGDRMGLL | |
| SCHEMBL6519201 | 0.83 | CHRM3 (0.67) | PTGIRCHRM3CHRM2CHRM1PTGDR | |
| SCHEMBL29019394 | 0.81 | PTGIR (0.57) | PTGIRCHRM3PTGDRMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003123-B | Modulators of the PGI2 receptor for the treatment of prostacyclin (PGI 2) receptor related disorders | 艾尼纳制药公司 | 2023-06-23 | — | — | CN | disclosed |