Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 18/20 | 0.68 |
| ▸ | EGFR | P00533 | 7/20 | 0.68 |
| ▸ | NUDT14 | O95848 | 2/20 | 0.63 |
| ▸ | NUDT5 | Q9UKK9 | 2/20 | 0.63 |
| ▸ | LCK | P06239 | 4/20 | 0.62 |
| ▸ | LYN | P07948 | 2/20 | 0.62 |
| ▸ | ITK | Q08881 | 4/20 | 0.61 |
| ▸ | TEC | P42680 | 2/20 | 0.57 |
| ▸ | TXK | P42681 | 2/20 | 0.57 |
| ▸ | BMX | P51813 | 2/20 | 0.57 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.57 |
| ▸ | LATS1 | O95835 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.57 |
| ▸ | FYN | P06241 | 1/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | CSF1R | P07333 | 1/20 | 0.57 |
| ▸ | YES1 | P07947 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29019597 | 0.97 | BTK (0.64) | BTKEGFRNUDT14NUDT5LCK | |
| SCHEMBL29019546 | 0.92 | BTK (0.60) | BTKEGFRNUDT14NUDT5LCK | |
| SCHEMBL22777861 | 0.90 | BTK (0.82) | BTKEGFRNUDT14NUDT5LCK | |
| SCHEMBL24196842 | 0.89 | BTK (0.61) | BTKEGFRNUDT14NUDT5LCK | |
| SCHEMBL30331346 | 0.89 | BTK (0.61) | BTKEGFRNUDT14NUDT5LCK | |
| SCHEMBL6430797 | 0.87 | BTK (0.77) | BTKEGFRNUDT14NUDT5LCK | |
| SCHEMBL22720866 | 0.87 | BTK (0.77) | BTKEGFRNUDT14NUDT5LCK | |
| SCHEMBL22721085 | 0.87 | BTK (0.77) | BTKEGFRNUDT14NUDT5LCK | |
| SCHEMBL25172544 | 0.86 | BTK (0.58) | BTKEGFRNUDT14NUDT5LCK | |
| SCHEMBL30415878 | 0.86 | BTK (0.58) | BTKEGFRNUDT14NUDT5LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134028-A | Compound capable of degrading BTK kinase, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2023-05-16 | — | — | CN | disclosed |