Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 11/20 | 0.53 |
| ▸ | ATF1 | P18846 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.46 |
| ▸ | BCL6 | P41182 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30395251 | 1.00 | CTSC (0.53) | CTSCATF1NFKB1AURKATRPV1 | |
| SCHEMBL655376 | 0.86 | AURKA (0.49) | CTSCATF1NFKB1AURKATRPV1 | |
| SCHEMBL270663 | 0.85 | DHODH (0.48) | ATF1NFKB1AURKATRPV1 | |
| SCHEMBL29019915 | 0.84 | CCNK (0.52) | CTSCAURKATRPV1BCL6 | |
| SCHEMBL30395248 | 0.84 | CCNK (0.52) | CTSCAURKATRPV1BCL6 | |
| SCHEMBL25179790 | 0.82 | CTSC (0.73) | CTSC | |
| SCHEMBL6923416 | 0.82 | CTSC (0.53) | CTSCAURKABCL6 | |
| SCHEMBL24842784 | 0.81 | CTSC (0.79) | CTSCAURKA | |
| SCHEMBL29816862 | 0.81 | CTSC (0.79) | CTSCAURKA | |
| SCHEMBL30395218 | 0.81 | CTSC (0.70) | CTSCAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111620852-B | 5-chloro-pyrimidine-2, 4-diamine compound, and preparation method and application thereof | 镇江植生源农业科技有限公司 | 2023-05-09 | — | — | CN | disclosed |