Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCND3 | P30281 | 1/20 | 0.51 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30395286 | 1.00 | CCND3 (0.51) | CCND3CDK6LMNAPOLBKDM4E | |
| SCHEMBL28715539 | 0.84 | USP10 (0.48) | LMNAKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL29392185 | 0.84 | USP10 (0.48) | LMNAKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL14662240 | 0.84 | APP (0.58) | LMNAKDM4EALDH1A1APPRAB9A | |
| SCHEMBL29019899 | 0.84 | CCNE2 (0.57) | CCND3CDK6LMNAPOLBTP53 | |
| SCHEMBL30395245 | 0.84 | CCNE2 (0.57) | CCND3CDK6LMNAPOLBTP53 | |
| SCHEMBL30394825 | 0.81 | PDE2A (0.56) | CCND3CDK6PDE2AAPP | |
| SCHEMBL29019891 | 0.81 | PDE2A (0.56) | CCND3CDK6PDE2AAPP | |
| SCHEMBL22261262 | 0.79 | JAK3 (0.57) | RAB9A | |
| SCHEMBL21588807 | 0.79 | CA1 (0.62) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111620852-B | 5-chloro-pyrimidine-2, 4-diamine compound, and preparation method and application thereof | 镇江植生源农业科技有限公司 | 2023-05-09 | — | — | CN | disclosed |