Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | RET | P07949 | 3/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 6/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29961651 | 1.00 | CLK1 (0.46) | CLK1MAPK1RETMETCNR1 | |
| SCHEMBL29020176 | 1.00 | CLK1 (0.46) | CLK1MAPK1RETMETCNR1 | |
| SCHEMBL29020204 | 0.94 | CLK1 (0.46) | CLK1MAPK1S1PR3S1PR4S1PR1 | |
| SCHEMBL29961565 | 0.94 | CLK1 (0.46) | CLK1MAPK1S1PR3S1PR4S1PR1 | |
| SCHEMBL29020202 | 0.94 | CLK1 (0.46) | CLK1MAPK1S1PR3S1PR4S1PR1 | |
| SCHEMBL29020159 | 0.90 | CLK1 (0.50) | CLK1MAPK1MET | |
| SCHEMBL29961667 | 0.90 | CLK1 (0.50) | CLK1MAPK1MET | |
| SCHEMBL29020156 | 0.90 | CLK1 (0.50) | CLK1MAPK1MET | |
| SCHEMBL29020222 | 0.89 | MAPK1 (0.52) | CLK1MAPK1METCNR1 | |
| SCHEMBL29020226 | 0.89 | MAPK1 (0.52) | CLK1MAPK1METCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093400-B | AhR inhibitor, application and preparation method thereof | 北京华森英诺生物科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-115093400-A | AhR inhibitor and application and preparation method thereof | 重庆华森制药股份有限公司 | 2022-09-23 | — | — | CN | disclosed |