Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 20/20 | 0.46 |
| ▸ | TYK2 | P29597 | 20/20 | 0.46 |
| ▸ | JAK2 | O60674 | 16/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | KIT | P10721 | 3/20 | 0.46 |
| ▸ | JAK3 | P52333 | 6/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24498258 | 0.85 | JAK1 (0.45) | JAK1TYK2JAK2KCNH2KIT | |
| SCHEMBL29684808 | 0.85 | JAK1 (0.45) | JAK1TYK2JAK2KCNH2KIT | |
| SCHEMBL30490073 | 0.84 | JAK1 (0.43) | JAK1TYK2JAK2KCNH2KIT | |
| SCHEMBL26527381 | 0.83 | TYK2 (0.45) | JAK1TYK2JAK2KCNH2KIT | |
| SCHEMBL29020411 | 0.82 | JAK1 (0.41) | JAK1TYK2JAK2KCNH2KIT | |
| SCHEMBL30385063 | 0.81 | TYK2 (0.41) | JAK1TYK2JAK2KCNH2KIT | |
| SCHEMBL29020387 | 0.81 | TYK2 (0.41) | JAK1TYK2JAK2KCNH2KIT | |
| SCHEMBL29684955 | 0.80 | JAK1 (0.44) | JAK1TYK2JAK2KCNH2KIT | |
| SCHEMBL24498256 | 0.80 | JAK1 (0.44) | JAK1TYK2JAK2KCNH2KIT | |
| SCHEMBL24498262 | 0.80 | JAK1 (0.49) | JAK1TYK2JAK2KCNH2KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901656-B | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-04-07 | — | — | CN | disclosed |