Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | USP2 | O75604 | 1/20 | 0.77 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL344191 | 0.89 | SMN1; SMN2 (0.96) | SMN1; SMN2USP2RECQLTSHRRAB9A | |
| SCHEMBL20448044 | 0.88 | SMN1; SMN2 (1.00) | SMN1; SMN2USP2RECQLTSHRRAB9A | |
| Acetic Acid SCHEMBL29118271 | 0.84 | SMN1; SMN2 (0.86) | SMN1; SMN2USP2RECQLTSHRRAB9A | |
| SCHEMBL392980 | 0.83 | SMN1; SMN2 (0.83) | SMN1; SMN2USP2RECQLTSHRPOLB | |
| SCHEMBL2920417 | 0.83 | SMN1; SMN2 (0.83) | SMN1; SMN2USP2RECQLTSHRRAB9A | |
| Formic Acid Methyl Ester SCHEMBL28770577 | 0.83 | HPGD (0.59) | SMN1; SMN2USP2RECQLRAB9AHPGD | |
| SCHEMBL28204425 | 0.81 | SMN1; SMN2 (0.80) | SMN1; SMN2USP2RECQLTSHRRAB9A | |
| SCHEMBL18084793 | 0.81 | SMN1; SMN2 (0.80) | SMN1; SMN2USP2RECQLTSHRRAB9A | |
| Formic Acid Methyl Ester SCHEMBL31257125 | 0.80 | USP2 (0.49) | SMN1; SMN2USP2RECQLHPGDGPR119 | |
| SCHEMBL12629406 | 0.79 | USP2 (0.76) | SMN1; SMN2USP2RECQLTSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107793409-B | Dihydropyrimidine compound and application thereof in medicine | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |