Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 17/20 | 0.52 |
| ▸ | CD274 | Q9NZQ7 | 17/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | F12 | P00748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30340518 | 0.87 | PDCD1 (0.43) | PDCD1CD274 | |
| SCHEMBL28595450 | 0.87 | PDCD1 (0.53) | PDCD1CD274HTR5A | |
| SCHEMBL30703794 | 0.85 | PDCD1 (0.42) | PDCD1CD274 | |
| SCHEMBL30966759 | 0.85 | PDCD1 (0.39) | PDCD1CD274 | |
| SCHEMBL30966761 | 0.84 | CYP1A2 (0.41) | PDCD1CD274DRD2HTR5A | |
| SCHEMBL27036516 | 0.84 | PDCD1 (0.53) | PDCD1CD274 | |
| SCHEMBL30966762 | 0.83 | PDCD1 (0.39) | PDCD1CD274DRD2HTR5A | |
| SCHEMBL31125637 | 0.83 | PDCD1 (0.38) | PDCD1CD274 | |
| SCHEMBL30566277 | 0.83 | PDCD1 (0.54) | PDCD1CD274 | |
| SCHEMBL30340703 | 0.83 | CNR2 (0.41) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112752756-B | Tetrahydro-imidazo [4,5-c ] pyridine derivatives as PD-L1 immunomodulators | 因赛特公司 | 2024-06-25 | — | — | CN | claimed |
| CN-118908978-A | Tetrahydro-imidazo [4,5-c ] pyridine derivatives as PD-L1 immunomodulators | 因赛特公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-112752756-B | Tetrahydro-imidazo [4,5-c ] pyridine derivatives as PD-L1 immunomodulators | 因赛特公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-113348170-B | Biphenyl derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-116115764-A | Tetrahydroimidazo [4,5-C ] pyridine derivatives as PD-L1 internalization inducers | 因赛特公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-112812113-B | Immunomodulatory compounds, compositions and uses thereof | 杭州和正医药有限公司 | 2022-09-20 | — | — | CN | disclosed |