SCHEMBL29023733

SCHEMBL29023733

CC(C=O)CSc1nc2ccccc2s1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.58
CYP2D6 P10635 3/20 0.58
CYP3A4 P08684 2/20 0.58
CYP2C19 P33261 2/20 0.58
MAPK1 P28482 2/20 0.58
HIF1A Q16665 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
APEX1 P27695 2/20 0.56
MAPT P10636 1/20 0.56
ALDH1A1 P00352 7/20 0.55
HPGD P15428 4/20 0.55
POLB P06746 2/20 0.55
RECQL P46063 1/20 0.55
CYP2C9 P11712 1/20 0.52
STAT6 P42226 1/20 0.52
HTR1A P08908 1/20 0.52
HTR2A P28223 1/20 0.52
HTR7 P34969 1/20 0.52
HSD17B10 Q99714 3/20 0.52
ALOX5 P09917 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29278087 0.87 CYP1A2 (0.65) CYP1A2CYP2D6CYP3A4CYP2C19MAPK1
SCHEMBL10989220 0.83 CYP1A2 (0.67) CYP1A2CYP2D6CYP3A4CYP2C19MAPK1
SCHEMBL10402125 0.83 APEX1 (0.64) CYP1A2CYP2D6CYP3A4CYP2C19MAPK1
SCHEMBL10403954 0.83 CYP1A2 (0.58) CYP1A2CYP2D6CYP3A4CYP2C19MAPK1
SCHEMBL3022330 0.81 CYP1A2 (0.63) CYP1A2CYP2D6CYP3A4CYP2C19MAPK1
SCHEMBL3026942 0.81 CYP1A2 (0.63) CYP1A2CYP2D6CYP3A4CYP2C19MAPK1
SCHEMBL3026939 0.81 CYP1A2 (0.63) CYP1A2CYP2D6CYP3A4CYP2C19MAPK1
SCHEMBL10037466 0.81 APEX1 (0.64) CYP1A2CYP2D6CYP3A4CYP2C19MAPK1
SCHEMBL3022326 0.81 CYP1A2 (0.63) CYP1A2CYP2D6CYP3A4CYP2C19MAPK1
Hydrochloric Acid SCHEMBL9097519 0.79 CYP1A2 (0.61) CYP1A2CYP2D6CYP3A4CYP2C19MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115947678-A Synthetic method of stable isotope 2H (D) labeled 25-hydroxy vitamin D2 成都诺森医学检验有限公司 2023-04-11 CN disclosed