Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 16/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 12/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20521201 | 0.81 | HDAC4 (0.66) | HDAC6HDAC4HDAC1HDAC8HDAC5 | |
| SCHEMBL21900100 | 0.81 | HDAC4 (0.60) | HDAC6HDAC4HDAC1HDAC8HDAC5 | |
| SCHEMBL21381196 | 0.80 | HDAC6 (0.60) | HDAC6HDAC4HDAC1HDAC8HDAC5 | |
| SCHEMBL23161794 | 0.80 | HDAC6 (0.54) | HDAC6HDAC4HDAC1HDAC8HDAC5 | |
| SCHEMBL20593670 | 0.80 | HDAC4 (0.65) | HDAC6HDAC4HDAC1HDAC8HDAC5 | |
| SCHEMBL23650886 | 0.79 | HDAC4 (0.59) | HDAC6HDAC4HDAC1HDAC8HDAC5 | |
| SCHEMBL21899971 | 0.79 | HDAC4 (0.56) | HDAC6HDAC4HDAC1HDAC8HDAC5 | |
| SCHEMBL23161732 | 0.79 | HDAC6 (0.59) | HDAC6HDAC4HDAC1HDAC8HDAC5 | |
| SCHEMBL23650101 | 0.79 | HDAC6 (0.61) | HDAC6HDAC4HDAC1HDAC8HDAC5 | |
| SCHEMBL23650427 | 0.79 | HDAC4 (0.60) | HDAC6HDAC4HDAC1HDAC8HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115955916-A | Active compound combinations | 拜耳公司 | 2023-04-11 | — | — | CN | disclosed |