Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2110069 | 1.00 | SIRT2 (0.51) | SIRT2GAALMNAALDH1A1HSD17B10 | |
| SCHEMBL9587057 | 1.00 | SIRT2 (0.51) | SIRT2GAALMNAALDH1A1HSD17B10 | |
| SCHEMBL2110034 | 1.00 | SIRT2 (0.51) | SIRT2GAALMNAALDH1A1HSD17B10 | |
| SCHEMBL2111698 | 1.00 | SIRT2 (0.51) | SIRT2GAALMNAALDH1A1HSD17B10 | |
| SCHEMBL2109882 | 1.00 | SIRT2 (0.51) | SIRT2GAALMNAALDH1A1HSD17B10 | |
| SCHEMBL2110751 | 1.00 | SIRT2 (0.51) | SIRT2GAALMNAALDH1A1HSD17B10 | |
| SCHEMBL2111446 | 1.00 | SIRT2 (0.51) | SIRT2GAALMNAALDH1A1HSD17B10 | |
| SCHEMBL2902851 | 1.00 | SIRT2 (0.51) | SIRT2GAALMNAALDH1A1HSD17B10 | |
| SCHEMBL10996586 | 1.00 | SIRT2 (0.51) | SIRT2GAALMNAALDH1A1HSD17B10 | |
| SCHEMBL8766498 | 1.00 | SIRT2 (0.51) | SIRT2GAALMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2725902-A2 | ANTI-VIRAL COMBINATION THERAPY | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2014-05-07 | — | — | EP | disclosed |
| WO-2012139028-A2 | ANTI-VIRAL COMBINATION THERAPY | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2012-10-11 | — | — | WO | disclosed |
| EP-2166843-A2 | TREATMENT OF VIRAL INFECTIONS BY MODULATION OF HOST CELL METABOLIC PATHWAYS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009023059-A2 | TREATMENT OF VIRAL INFECTIONS BY MODULATION OF HOST CELL METABOLIC PATHWAYS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2009-02-19 | — | — | WO | disclosed |