Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 15/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29025265 | 0.82 | MAP4K1 (0.46) | MAP4K1ALKJAK3LRRK2 | |
| SCHEMBL29894017 | 0.82 | MAP4K1 (0.46) | MAP4K1ALKJAK3LRRK2 | |
| SCHEMBL30462517 | 0.82 | MAP4K1 (0.49) | MAP4K1 | |
| SCHEMBL29025233 | 0.82 | MAP4K1 (0.49) | MAP4K1 | |
| SCHEMBL29025267 | 0.81 | MAP4K1 (0.49) | MAP4K1ALKJAK3LRRK2 | |
| SCHEMBL29025263 | 0.80 | MAP4K1 (0.47) | MAP4K1ALKJAK3LRRK2 | |
| SCHEMBL29025277 | 0.79 | MAP4K1 (0.48) | MAP4K1ALKJAK3LRRK2 | |
| SCHEMBL29025223 | 0.79 | MAP4K1 (0.48) | MAP4K1ALKJAK3LRRK2 | |
| SCHEMBL30462516 | 0.79 | MAP4K1 (0.47) | MAP4K1 | |
| SCHEMBL29025261 | 0.79 | MAP4K1 (0.47) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348117-A | HPK1 kinase inhibitor compounds | 杭州阿诺生物医药科技有限公司 | 2023-06-27 | — | — | CN | disclosed |
| WO-2022199561-A1 | HPK1 KINASE INHIBITOR COMPOUND | 杭州阿诺生物医药科技有限公司 | 2022-09-29 | — | — | WO | disclosed |