Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TPSAB1 | Q15661 | 5/20 | 0.51 |
| ▸ | TPSD1 | Q9BZJ3 | 5/20 | 0.51 |
| ▸ | TPSG1 | Q9NRR2 | 5/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26902832 | 1.00 | MAPT (0.54) | MAPTTPSAB1TPSD1TPSG1FOLH1 | |
| SCHEMBL30613463 | 1.00 | MAPT (0.54) | MAPTTPSAB1TPSD1TPSG1FOLH1 | |
| SCHEMBL26667474 | 0.87 | FOLH1 (0.63) | TPSAB1TPSD1TPSG1FOLH1HTT | |
| SCHEMBL26667478 | 0.87 | FOLH1 (0.63) | TPSAB1TPSD1TPSG1FOLH1HTT | |
| SCHEMBL24302720 | 0.83 | GAA (0.54) | TPSAB1TPSD1TPSG1FOLH1 | |
| SCHEMBL29717117 | 0.83 | GAA (0.54) | TPSAB1TPSD1TPSG1FOLH1 | |
| SCHEMBL26667473 | 0.83 | GAA (0.54) | TPSAB1TPSD1TPSG1FOLH1 | |
| SCHEMBL28337694 | 0.81 | MAPT (0.51) | MAPTTPSAB1TPSD1TPSG1FOLH1 | |
| SCHEMBL30613477 | 0.80 | FOLH1 (0.48) | TPSAB1TPSD1TPSG1FOLH1HTT | |
| SCHEMBL26902846 | 0.80 | FOLH1 (0.48) | TPSAB1TPSD1TPSG1FOLH1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116367832-A | Substituted heteroaryl compounds and uses thereof | 苏州华明道康生物医药有限公司 | 2023-06-30 | — | — | CN | disclosed |