SCHEMBL29025871

SCHEMBL29025871

Cc1cc(Nc2ncnc3ccc(NC(=O)/C=C/C4CCCN4C)cc23)ccc1Oc1ccc2nc[nH]c2c1

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EGFR P00533 18/20 0.68
ERBB2 P04626 17/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20780840 1.00 EGFR (0.68) EGFRERBB2
SCHEMBL20780771 0.91 EGFR (0.67) EGFRERBB2
SCHEMBL29025870 0.91 EGFR (0.67) EGFRERBB2
SCHEMBL22076845 0.85 ERBB2 (0.83) EGFRERBB2
SCHEMBL30478707 0.85 ERBB2 (0.83) EGFRERBB2
SCHEMBL20780802 0.85 ERBB2 (0.83) EGFRERBB2
SCHEMBL20780807 0.85 ERBB2 (0.83) EGFRERBB2
SCHEMBL30478675 0.85 ERBB2 (0.83) EGFRERBB2
SCHEMBL22076901 0.84 EGFR (0.66) EGFRERBB2
SCHEMBL22076900 0.84 EGFR (0.66) EGFRERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109422755-B Nitrogen-containing heterocyclic compound, preparation method, intermediate, composition and application 上海医药集团股份有限公司 2023-07-04 CN disclosed