Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.98 |
| ▸ | ATM | Q13315 | 19/20 | 0.98 |
| ▸ | PIK3CA | P42336 | 14/20 | 0.87 |
| ▸ | ATR | Q13535 | 4/20 | 0.87 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17272560 | 0.99 | MTOR (1.00) | MTORATMPIK3CAATRKCNH2 | |
| Trifluoroacetic Acid SCHEMBL17272524 | 0.93 | MTOR (0.89) | MTORATMPIK3CAATRKCNH2 | |
| SCHEMBL17272483 | 0.93 | ATM (1.00) | MTORATMPIK3CAATRKCNH2 | |
| SCHEMBL17272494 | 0.93 | ATM (1.00) | MTORATMPIK3CAATRKCNH2 | |
| SCHEMBL17272531 | 0.93 | ATM (1.00) | MTORATMPIK3CAATRKCNH2 | |
| SCHEMBL17242644 | 0.93 | ATM (1.00) | MTORATMPIK3CAATRKCNH2 | |
| SCHEMBL17242634 | 0.93 | ATM (1.00) | MTORATMPIK3CAATRKCNH2 | |
| SCHEMBL17272507 | 0.92 | ATM (1.00) | MTORATMPIK3CAATRKCNH2 | |
| SCHEMBL17242594 | 0.92 | ATM (1.00) | MTORATMPIK3CAATRKCNH2 | |
| SCHEMBL17242505 | 0.92 | ATM (1.00) | MTORATMPIK3CAATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116194109-A | Combination of antibody-drug conjugate and ATM inhibitor | 阿斯利康(英国)有限公司 | 2023-05-30 | — | — | CN | disclosed |