Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 known ✓ | P20309 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1037433 | 0.88 | CHRM3 (0.60) | CHRM3 | |
| SCHEMBL1037434 | 0.88 | CHRM3 (0.60) | CHRM3 | |
| SCHEMBL10147601 | 0.87 | CHRM3 (0.74) | CHRM3 | |
| Bromide SCHEMBL1042119 | 0.87 | CHRM3 (0.59) | CHRM3 | |
| SCHEMBL10147672 | 0.86 | CHRM3 (0.67) | CHRM3 | |
| Bromide SCHEMBL1041203 | 0.86 | CHRM3 (0.72) | CHRM3 | |
| Iodide SCHEMBL1039135 | 0.85 | CHRM3 (0.65) | CHRM3 | |
| Iodide SCHEMBL1042659 | 0.85 | CHRM3 (0.65) | CHRM3 | |
| Iodide SCHEMBL1040085 | 0.85 | CHRM3 (0.65) | CHRM3 | |
| SCHEMBL10147657 | 0.85 | CHRM3 (0.75) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2256117-A1 | Quiniclidine derivatives of (hetero) arylcycloheptanecarboxylic acid as muscarinic receptor antagonists | AstraZeneca AB (SE) | 2010-12-01 | — | — | EP | disclosed |