Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | ACP1 | P24666 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29028296 | 0.90 | PTPN1 (0.61) | PTPN1ACP1KDM4EPOLBMEN1 | |
| SCHEMBL29028292 | 0.83 | KDM4E (0.56) | PTPN1ACP1KDM4EPOLBMEN1 | |
| SCHEMBL29028279 | 0.83 | KDM4E (0.58) | PTPN1ACP1KDM4EPOLBMEN1 | |
| SCHEMBL29028286 | 0.80 | KDM4E (0.57) | PTPN1ACP1KDM4EPOLBMEN1 | |
| SCHEMBL29028387 | 0.80 | KMT2A (0.69) | PTPN1ACP1KDM4EPOLBMEN1 | |
| SCHEMBL29028291 | 0.79 | MEN1 (0.67) | PTPN1ACP1KDM4EPOLBMEN1 | |
| SCHEMBL29028307 | 0.78 | KMT2A (0.69) | PTPN1ACP1KDM4EPOLBMEN1 | |
| SCHEMBL29028359 | 0.77 | KMT2A (0.73) | PTPN1ACP1KDM4EPOLBMEN1 | |
| SCHEMBL29028351 | 0.77 | MEN1 (0.73) | PTPN1ACP1KDM4EPOLBMEN1 | |
| SCHEMBL29028333 | 0.76 | KMT2A (0.71) | PTPN1ACP1KDM4EPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354901-B | Thiazolidinedione compound and preparation method and application thereof | 郑州大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-116354901-A | Thiazolidinedione compound and preparation method and application thereof | 郑州大学 | 2023-06-30 | — | — | CN | disclosed |