SCHEMBL29029007

SCHEMBL29029007

CC(C)(C)c1ccc(C=CS)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.55
TSHR P16473 1/20 0.44
LMNA P02545 4/20 0.42
TYR P14679 1/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
TRPV1 Q8NER1 3/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPT P10636 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
GRIN2D O15399 2/20 0.41
GRIN3B O60391 2/20 0.41
GRIN1 Q05586 2/20 0.41
GRIN2A Q12879 2/20 0.41
GRIN2B Q13224 2/20 0.41
GRIN2C Q14957 2/20 0.41
GRIN3A Q8TCU5 2/20 0.41
HPGD P15428 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16900183 1.00 CYP1A2 (0.55) CYP1A2TSHRLMNATYRNPC1
SCHEMBL1825729 0.85 CYP1A2 (0.64) CYP1A2TSHRLMNATYRNPC1
SCHEMBL1825727 0.85 CYP1A2 (0.64) CYP1A2TSHRLMNATYRNPC1
SCHEMBL29145894 0.82 CYP1A2 (0.61) CYP1A2TSHRLMNATYRNPC1
SCHEMBL29349761 0.80 CYP1A2 (0.59) CYP1A2TSHRLMNATYRNPC1
SCHEMBL18843945 0.79 CYP1A2 (0.53) CYP1A2TSHRLMNATYRNPC1
SCHEMBL868821 0.78 CYP1A2 (0.57) CYP1A2TSHRLMNATYRNPC1
SCHEMBL868822 0.78 CYP1A2 (0.57) CYP1A2TSHRLMNATYRNPC1
SCHEMBL6546384 0.76 CYP1A2 (0.55) CYP1A2TSHRLMNANPC1RAB9A
SCHEMBL7535089 0.76 CYP1A2 (0.55) CYP1A2TSHRLMNANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957016-B Synthesis method of o-diamine compound 江南大学 2023-07-04 CN disclosed