Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK4 | Q16654 | 1/20 | 0.64 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | GRM1 | Q13255 | 10/20 | 0.50 |
| ▸ | GRM5 | P41594 | 9/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.46 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4249578 | 0.89 | PDK4 (0.65) | PDK4HTR6GRM1GRM5NAMPT | |
| SCHEMBL29149999 | 0.88 | PDK4 (0.67) | PDK4HTR6GRM1GRM5NAMPT | |
| SCHEMBL12712612 | 0.88 | PDK4 (0.69) | PDK4HTR6GRM1GRM5NAMPT | |
| SCHEMBL30432153 | 0.86 | PDK4 (0.64) | PDK4HTR6GRM1GRM5NAMPT | |
| SCHEMBL31321154 | 0.84 | PDK4 (0.60) | PDK4HTR6GRM1GRM5NAMPT | |
| SCHEMBL83700 | 0.84 | PDK4 (0.68) | PDK4HTR6GRM1GRM5NAMPT | |
| SCHEMBL30061046 | 0.84 | PDK4 (0.68) | PDK4HTR6GRM1GRM5NAMPT | |
| SCHEMBL4248631 | 0.84 | PDK4 (0.59) | PDK4HTR6GRM1GRM5NAMPT | |
| SCHEMBL31605660 | 0.83 | PDK4 (0.63) | PDK4HTR6GRM1GRM5NAMPT | |
| SCHEMBL30896738 | 0.83 | PDK4 (0.63) | PDK4HTR6GRM1GRM5NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217558-A | GLP-1 receptor agonist, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-06-06 | — | — | CN | disclosed |