Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK8 | O60259 | 20/20 | 0.59 |
| ▸ | F2 | P00734 | 20/20 | 0.59 |
| ▸ | KLKB1 | P03952 | 20/20 | 0.59 |
| ▸ | KLK14 | Q9P0G3 | 20/20 | 0.59 |
| ▸ | KLK5 | Q9Y337 | 20/20 | 0.59 |
| ▸ | ST14 | Q9Y5Y6 | 20/20 | 0.59 |
| ▸ | F10 | P00742 | 18/20 | 0.59 |
| ▸ | PLAU | P00749 | 12/20 | 0.59 |
| ▸ | ELANE | P08246 | 11/20 | 0.59 |
| ▸ | KLK1 | P06870 | 10/20 | 0.59 |
| ▸ | KLK7 | P49862 | 5/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29029647 | 0.81 | KLK8 (0.58) | KLK8F2KLKB1KLK14KLK5 | |
| SCHEMBL29029619 | 0.81 | KLK8 (0.58) | KLK8F2KLKB1KLK14KLK5 | |
| SCHEMBL28977229 | 0.81 | KLK8 (0.58) | KLK8F2KLKB1KLK14KLK5 | |
| SCHEMBL30359877 | 0.79 | KLK8 (0.59) | KLK8F2KLKB1KLK14KLK5 | |
| SCHEMBL28977227 | 0.79 | KLK8 (0.59) | KLK8F2KLKB1KLK14KLK5 | |
| SCHEMBL21585880 | 0.74 | KLK8 (1.00) | KLK8F2KLKB1KLK14KLK5 | |
| SCHEMBL26332072 | 0.72 | KLK8 (0.81) | KLK8F2KLKB1KLK14KLK5 | |
| SCHEMBL21585884 | 0.70 | KLK8 (1.00) | KLK8F2KLKB1KLK14KLK5 | |
| SCHEMBL21585889 | 0.70 | KLK8 (1.00) | KLK8F2KLKB1KLK14KLK5 | |
| SCHEMBL21585886 | 0.70 | KLK8 (1.00) | KLK8F2KLKB1KLK14KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217603-A | New compounds | 国家医疗保健研究所 | 2023-06-06 | — | — | CN | claimed |
| CN-116217603-A | New compounds | 国家医疗保健研究所 | 2023-06-06 | — | — | CN | disclosed |