Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 20/20 | 0.75 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29030991 | 1.00 | KHK (0.75) | KHKPDE10A | |
| SCHEMBL30567253 | 1.00 | KHK (0.75) | KHKPDE10A | |
| SCHEMBL29030931 | 0.92 | KHK (0.81) | KHKPDE10A | |
| SCHEMBL29030924 | 0.92 | KHK (0.81) | KHKPDE10A | |
| SCHEMBL30567265 | 0.92 | KHK (0.81) | KHKPDE10A | |
| SCHEMBL24239761 | 0.90 | KHK (0.82) | KHKPDE10A | |
| SCHEMBL23567035 | 0.90 | KHK (0.82) | KHKPDE10A | |
| SCHEMBL30016820 | 0.90 | KHK (0.82) | KHKPDE10A | |
| SCHEMBL24239775 | 0.90 | KHK (0.82) | KHKPDE10A | |
| SCHEMBL29031027 | 0.90 | KHK (0.77) | KHKPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354932-A | Pyrimidine derivative, preparation method and application thereof | 海思科医药集团股份有限公司 | 2023-06-30 | — | — | CN | disclosed |