Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 10/20 | 0.96 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29031858 | 1.00 | PARP1 (0.96) | PARP1SMN1; SMN2ALDH1A1KDM4EALOX15 | |
| SCHEMBL30472341 | 1.00 | PARP1 (0.96) | PARP1SMN1; SMN2ALDH1A1KDM4EALOX15 | |
| SCHEMBL30472346 | 1.00 | PARP1 (0.96) | PARP1SMN1; SMN2ALDH1A1KDM4EALOX15 | |
| SCHEMBL31014293 | 1.00 | PARP1 (0.96) | PARP1SMN1; SMN2ALDH1A1KDM4EALOX15 | |
| SCHEMBL28353399 | 1.00 | PARP1 (0.96) | PARP1SMN1; SMN2ALDH1A1KDM4EALOX15 | |
| SCHEMBL29031856 | 0.98 | PARP1 (1.00) | PARP1SMN1; SMN2ALDH1A1KDM4EALOX15 | |
| SCHEMBL20809207 | 0.94 | PARP1 (0.93) | PARP1SMN1; SMN2ALDH1A1KDM4EALOX15 | |
| SCHEMBL30472323 | 0.94 | PARP1 (0.93) | PARP1SMN1; SMN2ALDH1A1KDM4EALOX15 | |
| SCHEMBL14156164 | 0.77 | SMN1; SMN2 (0.74) | PARP1SMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL11641810 | 0.77 | SMN1; SMN2 (0.74) | PARP1SMN1; SMN2ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396206-A | Isoindolinone compound and preparation method and application thereof | 五邑大学 | 2023-07-07 | — | — | CN | disclosed |