⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30029374 | 1.00 | — | — | |
| SCHEMBL10426450 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL14237614 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL10413470 | 0.97 | — | — | |
| SCHEMBL31237597 | 0.97 | — | — | |
| Pyrazine SCHEMBL28143116 | 0.97 | HSP90AA1 (0.94) | — | |
| Benzene SCHEMBL27818129 | 0.94 | HSP90AA1 (0.89) | — | |
| Methyl Alcohol SCHEMBL8832417 | 0.92 | — | — | |
| Urea SCHEMBL27588147 | 0.87 | HSP90AA1 (0.76) | — | |
| Acetonitrile SCHEMBL1551418 | 0.85 | HSP90AA1 (0.73) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8428 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122059995-A | Organic-inorganic hybrid antimony halide and preparation method and application thereof | 洛阳师范学院 | 2026-05-19 | — | — | CN | claimed |
| CN-119679797-B | Application of 2-aminopyrazine derivative in preparation of medicine for treating and/or preventing cerebral apoplexy and complications | 中国药科大学 | 2026-05-15 | — | — | CN | claimed |
| US-20250223285-A1 | NOVEL HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS | JACOBIO PHARMACEUTICALS CO LTD (CN) | 2025-07-10 | — | — | US | claimed |
| CN-120118499-A | Polycarbonate alloy with laser direct structuring characteristic and preparation method thereof | 广东中塑新材料股份有限公司 | 2025-06-10 | — | — | CN | claimed |
| EP-3621604-B1 | SALT FORMS OF AMINO PYRAZINE PURINE BASED SELECTIVE KINASE INHIBITOR | FTG BIO LLC (US) | 2025-06-04 | — | — | EP | claimed |
| CN-120001342-A | PH responsive magnetic grading porous MOFs composite material and preparation method and application thereof | 德宏师范高等专科学校 | 2025-05-16 | — | — | CN | claimed |
| CN-120006267-A | Lead-free medium phosphorus chemical nickel plating solution | 珠海联鼎化工设备有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-119954733-A | Synthesis method of 3, 5-dibromo-2-aminopyrazine | 河北科技大学 | 2025-05-09 | — | — | CN | claimed |
| CN-119331480-B | Coating layer, secondary battery and electronic device | 宁德新能源科技有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-119056155-B | High-temperature flue gas filtering material and preparation method thereof | 江苏奥凯环保科技有限公司 | 2025-05-02 | — | — | CN | claimed |
| EP-0182277-A2 | Pyrazine diazohydroxide compounds and methods for their production and use | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 1986-05-28 | — | — | EP | claimed |
| US-4560756-A | 2-Aminopyrazines and the preparation of 2-aminopyrazines and pyrazines | BASF AKTIENGESELLSCHAFT (DE) | 1985-12-24 | — | — | US | claimed |
| EP-0111717-A2 | 2-Aminopyrazine and process for the preparation of 2-aminopyrazines and pyrazines | BASF Aktiengesellschaft (DE) | 1984-06-27 | — | — | EP | claimed |
| EP-0111160-A1 | Process for the preparation of 2-halogen and 2-cyano pyrazines | BASF Aktiengesellschaft (DE) | 1984-06-20 | — | — | EP | claimed |
| US-4301196-A | USING ACCELERATING OR DEPOLARIZING AGENTS WHICH ARE ORGANONITROGEN COMBOUNDS | KOLLMORGEN TECHNOLOGIES CORP. (US) | 1981-11-17 | — | — | US | claimed |
| EP-0018144-A1 | A process for the preparation of substituted 2-aminopyrazines | ELI LILLY AND COMPANY (US) | 1980-10-29 | — | — | EP | claimed |
| US-4211870-A | FROM AMINOACETONITRILE AND A PHENYL A-HALO OXIME | ELI LILLY AND COMPANY (US) | 1980-07-08 | — | — | US | claimed |
| US-3966726-A | Process for the production of cyclic carboxylic acid imides | AKZO N.V. (NL) | 1976-06-29 | — | — | US | claimed |
| US-3959277-A | Diimidazopyrazines and tetracarboxamidopyrazines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-05-25 | — | — | US | claimed |
| US-3932404-A | REACTION WITH AMMONIA AND A BASIC AGENT | PECHINEY UGINE KUHLMANN (FR) | 1976-01-13 | — | — | US | claimed |