Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.40 |
| ▸ | PIM1 | P11309 | 5/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.38 |
| ▸ | JAK2 | O60674 | 3/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.38 |
| ▸ | FLT3 | P36888 | 3/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | CSF1R | P07333 | 2/20 | 0.38 |
| ▸ | CLK2 | P49760 | 2/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.38 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26733229 | 1.00 | PRMT5 (0.40) | PRMT5WDR77PIM1DYRK1AJAK2 | |
| SCHEMBL29426504 | 0.81 | PRMT5 (0.42) | PRMT5WDR77PIM1DYRK1AJAK2 | |
| SCHEMBL24076263 | 0.81 | PRMT5 (0.42) | PRMT5WDR77PIM1DYRK1AJAK2 | |
| SCHEMBL26049203 | 0.77 | PRMT5 (0.38) | PRMT5WDR77PIM1DYRK1AJAK2 | |
| SCHEMBL26049201 | 0.77 | PRMT5 (0.38) | PRMT5WDR77PIM1DYRK1AJAK2 | |
| SCHEMBL17824559 | 0.75 | PRMT5 (0.45) | PRMT5WDR77PIM1DYRK1AJAK2 | |
| SCHEMBL30984977 | 0.73 | PRMT5 (0.46) | PRMT5WDR77PIM1DYRK1AJAK2 | |
| SCHEMBL25141683 | 0.73 | PRMT5 (0.46) | PRMT5WDR77PIM1DYRK1AJAK2 | |
| SCHEMBL24076903 | 0.73 | PRMT5 (0.48) | PRMT5WDR77PIM1DYRK1AJAK2 | |
| SCHEMBL17824774 | 0.72 | PRMT5 (0.46) | PRMT5WDR77PIM1DYRK1AJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261456-A | Compounds, compositions, and methods | 戴纳立制药公司 | 2023-06-13 | — | — | CN | disclosed |