Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | METAP2 | P50579 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1002281 | 0.85 | CYP1A2 (0.47) | BACE1BIRC5HTTNOS1METAP2 | |
| SCHEMBL30368774 | 0.85 | CYP1A2 (0.47) | BACE1BIRC5HTTNOS1METAP2 | |
| SCHEMBL26623571 | 0.81 | MALT1 (0.38) | BACE1BIRC5MALT1HTTLMNA | |
| SCHEMBL30628975 | 0.81 | MALT1 (0.38) | BACE1BIRC5MALT1HTTLMNA | |
| SCHEMBL15447338 | 0.81 | MALT1 (0.38) | BACE1BIRC5MALT1HTTLMNA | |
| SCHEMBL29033340 | 0.80 | EGFR (0.49) | HTTCSNK2A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL20528292 | 0.80 | BACE1 (0.47) | BACE1BIRC5MALT1HTTNOS1 | |
| SCHEMBL359616 | 0.77 | BACE1 (0.41) | BACE1BIRC5MALT1HTTNOS1 | |
| SCHEMBL30474837 | 0.77 | CYP1A2 (0.52) | BIRC5CYP1A2CYP2A6RAB9AKDM4E | |
| SCHEMBL22798606 | 0.76 | HTT (0.35) | BACE1BIRC5MALT1HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217478-A | Synthesis method of 6-amino-3-difluoromethyl quinoline | 苏州康润医药有限公司 | 2023-06-06 | — | — | CN | claimed |
| CN-116217478-A | Synthesis method of 6-amino-3-difluoromethyl quinoline | 苏州康润医药有限公司 | 2023-06-06 | — | — | CN | disclosed |