Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.54 |
| ▸ | IL6 | P05231 | 11/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26354824 | 1.00 | TLR7 (0.54) | TLR7IL6TLR8 | |
| SCHEMBL29034577 | 0.93 | TLR7 (0.57) | TLR7IL6TLR8 | |
| SCHEMBL26347740 | 0.92 | TLR7 (0.62) | TLR7IL6TLR8 | |
| SCHEMBL29034554 | 0.92 | TLR7 (0.51) | TLR7IL6TLR8 | |
| SCHEMBL26359820 | 0.91 | TLR7 (0.55) | TLR7IL6TLR8 | |
| SCHEMBL29034558 | 0.91 | TLR7 (0.52) | TLR7IL6TLR8 | |
| SCHEMBL26355904 | 0.91 | TLR7 (0.52) | TLR7IL6TLR8 | |
| SCHEMBL26355070 | 0.91 | TLR7 (0.60) | TLR7IL6TLR8 | |
| SCHEMBL26356048 | 0.91 | TLR7 (0.53) | TLR7IL6TLR8 | |
| SCHEMBL29475668 | 0.91 | TLR7 (0.57) | TLR7IL6TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116457023-A | antibody-TLR agonist conjugates, methods and uses thereof | AMBRX公司 | 2023-07-18 | — | — | CN | disclosed |