Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.52 |
| ▸ | PKM | P14618 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1699995 | 0.94 | MAPT (0.53) | MAPTPKMPOLBSMN1; SMN2TDP1 | |
| SCHEMBL29482091 | 0.94 | MAPT (0.53) | MAPTPKMPOLBSMN1; SMN2TDP1 | |
| SCHEMBL16038895 | 0.93 | MAPT (0.54) | MAPTPKMPOLBSMN1; SMN2TDP1 | |
| SCHEMBL28440217 | 0.90 | MAPT (0.51) | MAPTPKMPOLBSMN1; SMN2TDP1 | |
| SCHEMBL1700332 | 0.84 | MAPT (0.54) | MAPTPKMPOLBSMN1; SMN2TDP1 | |
| SCHEMBL29589101 | 0.83 | MAPT (0.53) | MAPTPKMPOLBSMN1; SMN2TDP1 | |
| SCHEMBL16037480 | 0.83 | MAPT (0.56) | MAPTPKMPOLBSMN1; SMN2TDP1 | |
| SCHEMBL16039835 | 0.83 | MAPT (0.53) | MAPTPKMPOLBSMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL22581377 | 0.82 | MAPT (0.52) | MAPTPKMPOLBSMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL29482106 | 0.82 | MAPT (0.52) | MAPTPKMPOLBSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116621860-A | Bcl-2 inhibitors | 广州麓鹏制药有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-111511748-B | Bcl-2 inhibitors | 广州麓鹏制药有限公司 | 2023-05-02 | — | — | CN | disclosed |