SCHEMBL29035191

SCHEMBL29035191

CC(C)(C)OC(=O)N1CC(c2ccc(F)cc2)C[C@@H]1CO

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 6/20 0.50
SRC P12931 8/20 0.42
RORC P51449 2/20 0.40
NR1H2 P55055 1/20 0.40
HTRA1 Q92743 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29523555 1.00 TACR1 (0.50) TACR1SRCRORCNR1H2HTRA1
SCHEMBL29523008 1.00 TACR1 (0.50) TACR1SRCRORCNR1H2HTRA1
SCHEMBL29035189 1.00 TACR1 (0.50) TACR1SRCRORCNR1H2HTRA1
SCHEMBL29035386 1.00 TACR1 (0.50) TACR1SRCRORCNR1H2HTRA1
SCHEMBL28534495 0.88 TACR1 (0.48) TACR1SRCRORCNR1H2
SCHEMBL21619693 0.88 TACR1 (0.48) TACR1SRCRORCNR1H2
SCHEMBL29200058 0.88 TACR1 (0.48) TACR1SRCRORCNR1H2
SCHEMBL20005800 0.88 TACR1 (0.41) TACR1SRCNR1H2
SCHEMBL21052736 0.88 TACR1 (0.41) TACR1SRCNR1H2
SCHEMBL21136410 0.88 TACR1 (0.41) TACR1SRCNR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116437913-A Pharmaceutical compounds for treating complement-mediated disorders 艾其林医药公司 2023-07-14 CN disclosed