Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 4/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29035259 | 1.00 | MEN1 (0.37) | MEN1KMT2AUCHL1SRCUSP30 | |
| SCHEMBL29035412 | 0.93 | MEN1 (0.36) | MEN1KMT2AUCHL1USP30 | |
| SCHEMBL29035415 | 0.93 | MEN1 (0.36) | MEN1KMT2AUCHL1USP30 | |
| SCHEMBL25363576 | 0.91 | DPP4 (0.41) | MEN1KMT2AUCHL1GPR119NR1H2 | |
| SCHEMBL25363581 | 0.91 | DPP4 (0.41) | MEN1KMT2AUCHL1GPR119NR1H2 | |
| SCHEMBL30571864 | 0.91 | GBA1 (0.40) | MEN1KMT2AUCHL1CKS1BSKP1 | |
| SCHEMBL25364059 | 0.89 | SMYD2 (0.36) | SMYD2 | |
| SCHEMBL25364066 | 0.89 | SMYD2 (0.36) | SMYD2 | |
| SCHEMBL29035317 | 0.88 | MEN1 (0.34) | MEN1KMT2AUCHL1USP30SMYD2 | |
| SCHEMBL29035318 | 0.88 | MEN1 (0.34) | MEN1KMT2AUCHL1USP30SMYD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4216946-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Achillion Pharmaceuticals, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| CN-116437913-A | Pharmaceutical compounds for treating complement-mediated disorders | 艾其林医药公司 | 2023-07-14 | — | — | CN | disclosed |
| WO-2022066774-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2022-03-31 | — | — | WO | disclosed |